Scheiflinger, F.: search on Z-Library

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1

Mining ancient proteins for next-generation drugs

Lazarus, Robert A, Scheiflinger, Friedrich

Journal:

Nature Biotechnology

Year:

2017

Language:

english

File:

PDF, 543 KB

english, 2017

2

Ca2+concentration-dependent conformational change of FVIII B-domain observed by atomic force microscopy

Bonazza, Klaus, Rottensteiner, Hanspeter, Schrenk, Gerald, Fiedler, Christian, Scheiflinger, Friedrich, Allmaier, Günter, Turecek, Peter L., Friedbacher, Gernot

Journal:

Analytical and Bioanalytical Chemistry

Year:

2015

File:

PDF, 9.02 MB

2015

3

Higher expression of fab antibody fragments in a CHO cell line at reduced temperature

Simone M. Schatz, Randolf J. Kerschbaumer, Gabriele Gerstenbauer, Martina Kral, Friedrich Dorner, Friedrich Scheiflinger

Journal:

Biotechnology and Bioengineering

Year:

2003

Language:

english

File:

PDF, 226 KB

english, 2003

4

Comparative analysis of marketed factor VIII products: recombinant products are not alike vis-a-vis soluble protein aggregates and subvisible particles

Anzengruber, J., Lubich, C., Prenninger, T., Gringeri, A., Scheiflinger, F., Reipert, B. M., Malisauskas, M.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2018

Language:

english

File:

PDF, 411 KB

english, 2018

5

The Mystery of Antibodies Against Polyethylene Glycol (PEG) - What do we Know?

Lubich, Christian, Allacher, Peter, de la Rosa, Maurus, Bauer, Alexander, Prenninger, Thomas, Horling, Frank Michael, Siekmann, Jürgen, Oldenburg, Johannes, Scheiflinger, Friedrich, Reipert, Birgit Ma

Journal:

Pharmaceutical Research

Year:

2016

Language:

english

File:

PDF, 3.90 MB

english, 2016

6

Optimization of an Antibody Light Chain Framework Enhances Expression, Biophysical Properties and Pharmacokinetics

Douillard, Patrice, Freissmuth, Michael, Antoine, Gerhard, Thiele, Michael, Fleischanderl, Daniel, Matthiessen, Peter, Voelkel, Dirk, Kerschbaumer, Randolf J., Scheiflinger, Friedrich, Sabarth, Nicola

Journal:

Year:

2019

Language:

english

File:

PDF, 2.76 MB

english, 2019

7

Screening of complex fucoidans from four brown algae species as procoagulant agents

Zhang, Zhenqing, Till, Susanne, Knappe, Sabine, Quinn, Catherine, Catarello, James, Ray, G. Joseph, Scheiflinger, Friedrich, Szabo, Christina M., Dockal, Michael

Journal:

Carbohydrate Polymers

Year:

2015

Language:

english

File:

PDF, 776 KB

english, 2015

8

Structure-activity relationship of the pro- and anticoagulant effects of Fucus vesiculosus fucoidan

Zhang, Z., Till, S., Jiang, C., Knappe, S., Reutterer, S., Scheiflinger, F., Szabo, C. M., Dockal, M.

Journal:

Thrombosis and Haemostasis

Year:

2013

Language:

english

File:

PDF, 783 KB

english, 2013

9

In-depth comparison of N -glycosylation of human plasma-derived factor VIII and different recombinant products: from structure to clinical implications

Canis, K., Anzengruber, J., Garenaux, E., Feichtinger, M., Benamara, K., Scheiflinger, F., Savoy, L.-A., Reipert, B.M., Malisauskas, M.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2018

Language:

english

File:

PDF, 801 KB

english, 2018

10

Microchip capillary gel electrophoresis of multiply PEGylated high-molecular-mass glycoproteins

Birgit K. Seyfried, Martina Marchetti-Deschmann, Jürgen Siekmann, Mary J. Bossard, Friedrich Scheiflinger, Peter L. Turecek, Prof. Günter Allmaier

Journal:

Biotechnology Journal

Year:

2012

Language:

english

File:

PDF, 179 KB

english, 2012

11

VH1-69 germline encoded antibodies directed towards ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura

W. POS, B. M. LUKEN, J. A. KREMER HOVINGA, E. A. M. TURENHOUT, F. SCHEIFLINGER, J.-F. DONG, R. FIJNHEER, J. VOORBERG

Journal:

Journal of Thrombosis and Haemostasis

Year:

2009

Language:

english

File:

PDF, 677 KB

english, 2009

12

Inverse correlation of free and immune complex-sequestered anti-ADAMTS13 antibodies in a patient with acquired thrombotic thrombocytopenic purpura

S. FERRARI, P. KNÖBL, V. KOLOVRATOVA, B. PLAIMAUER, P. L. TURECEK, K. VARADI, H. ROTTENSTEINER, F. SCHEIFLINGER

Journal:

Journal of Thrombosis and Haemostasis

Year:

2012

Language:

english

File:

PDF, 160 KB

english, 2012

13

A new vaccinia recombinant plasmid pSC-O

Scheiflinger, Fritz, Bodemer, Walter

Journal:

Year:

1991

Language:

english

File:

PDF, 179 KB

english, 1991

14

Direct inhibition of factor VIIa by TFPI and TFPI constructs

Peraramelli, S., Thomassen, S., Heinzmann, A., Rosing, J., Hackeng, T. M., Hartmann, R., Scheiflinger, F., Dockal, M.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2013

Language:

english

File:

PDF, 410 KB

english, 2013

15

The biological efficacy profile of BAX 855, a PEGylated recombinant factor VIII molecule

Valentino, L. A., Cong, L., Enockson, C., Song, X., Scheiflinger, F., Muchitsch, E. M., Turecek, P. L., Hakobyan, N.

Journal:

Year:

2015

Language:

english

File:

PDF, 290 KB

english, 2015

16

Development of Methods for the Selective Measurement of the Single Amino Acid Exchange Variant Coagulation Factor IX Padua

Weber, Alfred, Engelmaier, Andrea, Voelkel, Dirk, Pachlinger, Robert, Scheiflinger, Friedrich, Monahan, Paul E., Rottensteiner, Hanspeter

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2018

Language:

english

File:

PDF, 1.20 MB

english, 2018

17

Structural analysis of the recombinant therapeutic product rFVIII and its PEGylated variants using 2-D DIGE

Christina Monetti, Hanspeter Rottensteiner, Herbert Gritsch, Alfred Weber, Friedrich Scheiflinger, Peter L. Turecek

Journal:

ELECTROPHORESIS

Year:

2011

Language:

english

File:

PDF, 558 KB

english, 2011

18

ADAMTS13 gene defects in two brothers with constitutional thrombotic thrombocytopenic purpura and normalization of von Willebrand factor-cleaving protease activity by recombinant human ADAMTS13

Gerhard Antoine, Klaus Zimmermann, Barbara Plaimauer, Monika Grillowitzer, Jan-Dirk Studt, Bernhard Lämmle, Friedrich Scheiflinger

Journal:

British Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 68 KB

english, 2003

19

Differences in N-glycosylation of recombinant human coagulation factor VII derived from BHK, CHO, and HEK293 cells

Böhm, Ernst, Seyfried, Birgit K., Dockal, Michael, Graninger, Michael, Hasslacher, Meinhard, Neurath, Marianne, Konetschny, Christian, Matthiessen, Peter, Mitterer, Artur, Scheiflinger, Friedrich

Journal:

BMC Biotechnology

Year:

2015

Language:

english

File:

PDF, 3.92 MB

english, 2015

20

Temperature‐dependent irreversible conformational change of recombinant ADAMTS13 upon metal ion chelation

Rottensteiner, Hanspeter, Kaufmann, Stefan, Rathgeb, Anna, Kink, Barbara, Plaimauer, Barbara, Matthiessen, Peter, Hann, Stephan, Scheiflinger, Friedrich

Journal:

Journal of Thrombosis and Haemostasis

Year:

2019

Language:

english

File:

PDF, 877 KB

english, 2019

21

Immunochemical detection of prion protein on dipsticks prepared with crystalline bacterial cell-surface layers

Dirk Völkel, Klaus Zimmermann, Andreas Breitwieser, Sabrina Pable, Markus Glatzel, Friedrich Scheiflinger, Hans P. Schwarz, Margit Sara, Uwe B. Sleytr, Friedrich Dorner

Journal:

Transfusion (Wiley)

Year:

2003

Language:

english

File:

PDF, 102 KB

english, 2003

22

Recombinant ADAMTS13 normalizes von Willebrand factor-cleaving activity in plasma of acquired TTP patients by overriding inhibitory antibodies

B. PLAIMAUER, J. A. KREMER HOVINGA, C. JUNO, M. J. WOLFSEGGER, S. SKALICKY, M. SCHMIDT, L. GRILLBERGER, M. HASSLACHER, P. KNÖBL, H. EHRLICH, F. SCHEIFLINGER

Journal:

Journal of Thrombosis and Haemostasis

Year:

2011

Language:

english

File:

PDF, 286 KB

english, 2011

23

Development of an in vitro biopotency assay for an AAV8 hemophilia B gene therapy vector suitable for clinical product release

Lengler, Johannes, Coulibaly, Sogue, Gruber, Bernadette, Ilk, Reinhard, Mayrhofer, Josef, Scheiflinger, Friedrich, Hoellriegl, Werner, Falkner, Falko G., Rottensteiner, Hanspeter

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2020

Language:

english

File:

PDF, 4.22 MB

english, 2020

24

Species-dependent variability of ADAMTS13-mediated proteolysis of human recombinant von Willebrand factor

K. VARADI, H. ROTTENSTEINER, S. VEJDA, A. WEBER, E.-M. MUCHITSCH, P. L. TURECEK, H. J. EHRLICH, F. SCHEIFLINGER, H. P. SCHWARZ

Journal:

Journal of Thrombosis and Haemostasis

Year:

2009

Language:

english

File:

PDF, 412 KB

english, 2009

25

Shear-dependent interactions of von Willebrand Factor with Factor VIII and protease ADAMTS 13 demonstrated at a single molecule level by Atomic Force Microscopy

Bonazza, Klaus, Rottensteiner, Hanspeter, Schrenk, Gerald, Frank, Johannes, Allmaier, Günter, Turecek, Peter L., Scheiflinger, Friedrich, Friedbacher, Gernot

Journal:

Analytical Chemistry

Year:

2015

Language:

english

File:

PDF, 1.74 MB

english, 2015

26

COMPARISON OF CYTOKINE RESPONSE IN DIFFERENT MOUSE STRAINS AND SEPSIS MODELS

MUCHITSCH, E. M., ZIMMERMANN, K, KUBIK, S. M., SCHWARZ, H. P., SCHEIFLINGER, F

Journal:

Year:

2004

File:

PDF, 139 KB

2004

27

The detection of biologically relevant low-titer neutralizing antibodies against AAV require sensitive in vitro assays

Kruzik, Anita, Koppensteiner, Herwig, Fetahagic, Damir, Hartlieb, Bettina, Dorn, Sebastian, Romeder-Finger, Stefan, Coulibaly, Sogué, Weber, Alfred, Höllriegl, Werner, Horling, Frank M, Scheiflinger,

Journal:

Human Gene Therapy Methods

Year:

2019

Language:

english

File:

PDF, 982 KB

english, 2019

28

How Full-Length FVIII Benefits from Its Heterogeneity – Insights into the Role of the B-Domain

Anzengruber, Julia, Feichtinger, Martin, Bärnthaler, Philipp, Haider, Norbert, Ilas, Josenato, Pruckner, Nina, Benamara, Karima, Scheiflinger, Friedrich, Reipert, Birgit M., Malisauskas, Mantas

Journal:

Pharmaceutical Research

Year:

2019

Language:

english

File:

PDF, 2.27 MB

english, 2019

29

Structural and Functional Studies of the Measles Virus Hemagglutinin: Identification of a Novel Site Required for CD46 Interaction

John B. Patterson, Friedrich Scheiflinger, Marianne Manchester, Tilahun Yilma, Michael B.A. Oldstone

Journal:

Year:

1999

Language:

english

File:

PDF, 369 KB

english, 1999

30

A novel flow-based assay reveals discrepancies in ADAMTS-13 inhibitor assessment as compared with a conventional clinical static assay

Grillberger, R., Gruber, B., Skalicky, S., Schrenk, G., Knöbl, P., Plaimauer, B., Turecek, P. L., Scheiflinger, F., Rottensteiner, H.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2014

Language:

english

File:

PDF, 484 KB

english, 2014

31

Human Anti-Macrophage Migration Inhibitory Factor Antibodies Inhibit Growth of Human Prostate Cancer Cells In Vitro and In Vivo

Hussain, F., Freissmuth, M., Volkel, D., Thiele, M., Douillard, P., Antoine, G., Thurner, P., Ehrlich, H., Schwarz, H.-P., Scheiflinger, F., Kerschbaumer, R. J.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 740 KB

english, 2013

32

Comparative analysis of marketed factor VIII products: reply

Reipert, Birgit M., Anzengruber, Julia, Scheiflinger, Friedrich

Journal:

Journal of Thrombosis and Haemostasis

Year:

2018

Language:

english

File:

PDF, 131 KB

english, 2018

33

Characterization of the vaccinia MVA hemagglutinin gene locus and its evaluation as an insertion site for foreign genes

Gerhard Antoine, Friedrich Scheiflinger, Georg Holzer, Thomas Langmann, Falko G. Falkner, Friedrich Dorner

Journal:

Year:

1996

Language:

english

File:

PDF, 427 KB

english, 1996

34

811: Fully human antibodies specific for oxidized macrophage migration inhibitory factor (oxMIF) exhibit anti-cancer activity in animal models

Thiele, M., Hagemann, T., Freissmuth, M., Douillard, P., Völkel, D., Scheiflinger, F., Kerschbaumer, R.J.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 64 KB

english, 2014

35

[IEEE 2013 Integrated Communications, Navigation and Surveillance Conference (ICNS) - Herndon, VA, USA (2013.04.22-2013.04.25)] 2013 Integrated Communications, Navigation and Surveillance Conference (ICNS) - Implementation of a nationwide wide-area multilateration system for Austrian Airspace

Langhans, Werner, Scheiflinger, Christian, Weidner, Wolfgang, Auer, Joachim, Fitzgerald, Patrick, Anzalone, Michael

Year:

2013

Language:

english

File:

PDF, 1.32 MB

english, 2013

36

Plasmatic tissue factor pathway inhibitor is a major determinant of clotting in factor VIII inhibited plasma or blood

Knappe, Sabine, Gorczyca, Monika, Jilma, Bernd, Derhaschnig, Ulla, Hartmann, Rudolf, Palige, Michael, Scheiflinger, Fritz, Dockal, Michael

Journal:

Thrombosis and Haemostasis

Year:

2013

Language:

english

File:

PDF, 505 KB

english, 2013

37

Corrigendum to “The complete genomic sequence of the modified vaccinia Ankara (MVA) strain: Comparison with other orthopoxviruses” [Virology 244 (1998) 365-396]

G. Antoine, F. Scheiflinger, F. Dorner, F.G. Falkner

Journal:

Year:

2006

Language:

english

File:

PDF, 50 KB

english, 2006

38

P078 Efficacy of human anti-macrophage migration inhibitory factor antibodies in mouse models of inflammatory bowel disease

Thiele, M., Magelky, E., Schinagl, A., Völkel, D., Douillard, P., Ehrlich, H., Scheiflinger, F., Kerschbaumer, R., Terhorst, C.

Journal:

Journal of Crohn's and Colitis

Year:

2013

Language:

english

File:

PDF, 55 KB

english, 2013

39

Identification of cysteine thiol‐based linkages in ADAMTS13 in support of a non‐proteolytic regulation of von Willebrand factor

Rottensteiner, Hanspeter, Seyfried, Birgit K., Kaufmann, Stefan, Fiedler, Christian, Dong, Jing‐Fei, Zheng, X. Long, Plaimauer, Barbara, Scheiflinger, Friedrich

Journal:

Journal of Thrombosis and Haemostasis

Year:

2019

Language:

english

File:

PDF, 647 KB

english, 2019

40

Structural analysis of the recombinant therapeutic product rFVIII and its PEGylated variants using 2-D DIGE

Christina Monetti, Hanspeter Rottensteiner, Herbert Gritsch, Alfred Weber, Friedrich Scheiflinger, Peter L. Turecek

Journal:

PROTEOMICS - Clinical Applications

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

41

Patterns of changes of anti-ADAMTS13 after plasma exchange

P. M. MANNUCCI, M. BÖHM, I. SCHARRER, F. SCHEIFLINGER

Journal:

Journal of Thrombosis and Haemostasis

Year:

2006

Language:

english

File:

PDF, 117 KB

english, 2006

42

Anti-ADAMTS13 IgG autoantibodies present in healthy individuals share linear epitopes with those in patients with thrombotic thrombocytopenic purpura

Grillberger, R., Casina, V. C., Turecek, P. L., Zheng, X. L., Rottensteiner, H., Scheiflinger, F.

Journal:

Year:

2014

Language:

english

File:

PDF, 670 KB

english, 2014

43

Cloning, expression and functional characterization of the full-length murine ADAMTS13

K. BRUNO, D. VÖLKEL, B. PLAIMAUER, G. ANTOINE, S. PABLE, D. G. MOTTO, H. L. LEMMERHIRT, F. DORNER, K. ZIMMERMANN, F. SCHEIFLINGER

Journal:

Journal of Thrombosis and Haemostasis

Year:

2005

Language:

english

File:

PDF, 779 KB

english, 2005

44

Inhibition of tissue factor:factor VIIa-catalyzed factor IX and factor X activation by TFPI and TFPI constructs

Peraramelli, S., Thomassen, S., Heinzmann, A., Rosing, J., Hackeng, T. M., Hartmann, R., Scheiflinger, F., Dockal, M.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2014

Language:

english

File:

PDF, 684 KB

english, 2014

45

A patient with SLE-associated thrombotic microangiopathy and non-neutralizing antibodies against ADAMTS13

Knecht, M. E., Mayr, M., Ferrari, S., Scheiflinger, F., Trendelenburg, M.

Journal:

Nephrology Dialysis Transplantation

Year:

2010

Language:

english

File:

PDF, 77 KB

english, 2010

46

Genome editing for scalable production of alloantigen‐free lentiviral vectors for in vivo gene therapy

Milani, Michela, Annoni, Andrea, Bartolaccini, Sara, Biffi, Mauro, Russo, Fabio, Di Tomaso, Tiziano, Raimondi, Andrea, Lengler, Johannes, Holmes, Michael C, Scheiflinger, Friedrich, Lombardo, Angelo,

Journal:

EMBO Molecular Medicine

Year:

2017

Language:

english

File:

PDF, 1.52 MB

english, 2017

47

PEGylated recombinant von Willebrand factor analyzed by means of MALDI-TOF-MS, CGE-on-a-chip and nES-GEMMA

Birgit K. Seyfried, Jürgen Siekmann, Peter L. Turecek, Hans Peter Schwarz, Friedrich Scheiflinger, Harold Zappe, Mary L. Bossard, Günter Allmaier

Journal:

International Journal of Mass Spectrometry

Year:

2011

Language:

english

File:

PDF, 514 KB

english, 2011

48

Aptamer BAX 499 mediates inhibition of tissue factor pathway inhibitor via interaction with multiple domains of the protein

Waters, E. K., Genga, R. M., Thomson, H. A., Kurz, J. C., Schaub, R. G., Scheiflinger, F., McGinness, K. E.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2013

Language:

english

File:

PDF, 346 KB

english, 2013

49

Potential for Recombinant ADAMTS13 as an Effective Therapy for Acquired Thrombotic Thrombocytopenic Purpura

Tersteeg, Claudia, Schiviz, Alexandra, De Meyer, Simon F., Plaimauer, Barbara, Scheiflinger, Friedrich, Rottensteiner, Hanspeter, Vanhoorelbeke, Karen

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

50

Flow-induced elongation of von Willebrand factor precedes tension-dependent activation

Fu, Hongxia, Jiang, Yan, Yang, Darren, Scheiflinger, Friedrich, Wong, Wesley P., Springer, Timothy A.

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 1.84 MB

english, 2017

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